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Symbol
Name
ID

Pdgfrb
platelet derived growth factor receptor, beta polypeptide
MGI:97531

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Calcification of the small brain vessels

Cerebellar calcifications

Cerebellar dentate nucleus calcification

Cerebral calcification

Basal ganglia calcification

Thalamic calcification

Benign neoplasm of the central nervous system

Dysdiadochokinesis

Limb dysmetria

Bradykinesia

Parkinsonism

Athetosis

Chorea

Tremor

Postural tremor

Hand tremor

Abnormal pyramidal sign

Hemiplegia/hemiparesis

Dysarthria

Depression

Anxiety

Psychosis

Bipolar affective disorder

Apathy

Impaired executive functioning

Motor tics

Attention deficit hyperactivity disorder

Cognitive impairment

Memory impairment

Mental deterioration

Dementia

Micrographia

Hyperreflexia

Dyskinesia

Dystonia

Gait disturbance

Postural instability

Migraine

Global developmental delay

Seizure

Disease(s) Associated with PDGFRB

basal ganglia calcification

infantile myofibromatosis

Mouse Phenotypes		intracranial hemorrhage	increased susceptibility to neuronal excitotoxicity	decreased neuron number	decreased retina ganglion cell number	retina ganglion cell degeneration	abnormal blood-retina barrier function	abnormal nervous system electrophysiology	reduced sensorimotor gating	decreased prepulse inhibition
Availability	Mouse Genotype	intracranial hemorrhage	increased susceptibility to neuronal excitotoxicity	decreased neuron number	decreased retina ganglion cell number	retina ganglion cell degeneration	abnormal blood-retina barrier function	abnormal nervous system electrophysiology	reduced sensorimotor gating	decreased prepulse inhibition
	Pdgfrb^redeye/Pdgfrb^redeye
	Pdgfrb^tm10Sor/Pdgfrb^tm10Sor
	Pdgfrb^tm1Msas/Pdgfrb^tm1Msas Tg(Nes-cre)1Nogu/? (conditional)
	Pdgfrb^tm1Msas/Pdgfrb^tm1Msas Tg(Nes-cre)1Nogu/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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